الأوراق العلمية


عرضالصفحاتعنوان الورقة +الملخصر.م
من 1 ـــ الي 4
الملخص

not found

1
من 5 ـــ الي 11
الملخص

not found

2
من 12 ـــ الي 19
3
من 20 ـــ الي 25
الملخص

not found

4
من 26 ـــ الي 32
5
من 33 ـــ الي 37
6
من 38 ـــ الي 42
الملخص

The decisions determining the type of surgery for rectal carcinoma require an exact pre-operative assessment of the tumour and its lymph mode involvement. To determine which tumour features that can predict LNM (lymph node metastases), fifty rectal carcinomas treated by conventional curative resection were studied with flow-cytometric measurement of DNA ploidy and DNA index. Routine pathology reports provided a measure of tumour size, tumour differentiation and depth of tumour invasion. 16 (32%) of the patients had LNM. Tumour size was not associated with LNM (Mann-Whitney U test, P=0.795). There was trend toward an association between poorer differentiation and LNM (X2=5.895, df=2, P=0.0525). Invasion through the bowel wall was associated with LNM (X2=6.494, df=l, P=0.011). Ploidy was not associated with LNM (X2=2.21, df=1, P=0.138), however DNA index of greater than 1.5 was significantly associated with LNM (X2=6.359, df=l, P=0.012). Furthermore, analyzing tumour DNA ploidy at the same depth of invasion, the incidence of LNM was significantly higher in aneuploid tumours than diploid tumours (X2 =9.190, df=3, P=0.027). The result of this study suggests that pre-operative FCM analysis of DNA content of rectal cancer from biopsy sample could be useful in evaluating the status of LNM, and therefore could provide important information that may determine the type of surgery.

7
من 43 ـــ الي 46
الملخص

This study was conducted to assess in Libyan females the incidence of catamenial epilepsy. This form of epilepsy is defined as the increase in seizure frequency in relation to the menstrual cycle. We also evaluated retrospectively the pattern of seizures, and the drug management of these patients using acetazolamide as an add-on drug or by increasing the dose of the usual antiepileptic drug (AED). The preliminary results have demonstrated that the incidence of catamenial epilepsy among Libyan females studied was 8.83 %.The period prevalence for the exacerbation of the seizures was during the perimenstrual phase and during the entire second half of the cycle (60.19%). Catamenial seizures were more common (79.61%) among women with complex partial type of seizure. Acetazolamide was effective in improving the conditions of patients with catamenial epilepsy . In 88.89% the number of seizures was reduced by more than 50%, and the combination was as effective as using multiple drug therapy based on combination of more than one AED (89.39%).

8
من 47 ـــ الي 54
9
من 55 ـــ الي 61
الملخص

Dapsone is a drug that is effectively used in the treatment of a variety of infectious diseases such as leprosy and malaria, also in inflammatory disorders like dermatitis herpetiformis. The N-hydroxylated metabolites of dapsone are responsible for most of its adverse reactions. The present study aims to evaluate the role of one of the inhibitors of oxidative metabolism, cimetidine, on dapsone induced haemotoxicity in rats. The treated experimental animals were divided into 4 groups. The first and third groups were receiving a dose of 10mg/Kg dapsone alone by gavage once and twice daily respectively for 4 weeks. The second and fourth groups were dosed as in the first and third groups, except that cimetidine (40 mg/Kg) was given by gavage one hour before each dapsone dose. The results of the study revealed significant increase in met Hb% in dapsone treated groups compared with the control group, which was dose-dependent (12.73 ± 1.79 and 26.22 ± 2.87 in the first and third groups respectively). There was significant decrease in met Hb% of the second group compared with the first group (3.80J± 0.8 Vs 12.73 ± 1.7i)) which could be attributed to the metabolic inhibitory effect of cimetidine. With higher doses of dapsone, cimetidine did not have the same metHb reduced effect as metHb was insignificantly decreased in the fourth group compared with the third group (23.59 ± 3.36 Vs 26.22 ± 2.87). There was also significant reduction in haemoglobin and red blood cell count (haemolysis) and neutrophil count (agranulocytosis) in dapsone treated groups, which was dose dependent and not alleviated by co-administration of cimetidine. From the study, it can be concluded that although cimetidine may reduce metHb formation during prolonged dapsone administration, dose reduction of dapsone is required to avoid haemotoxicity because of the increased accumulation of both parent drug and its metabolites. Also, one should take care about "therapy efficiency/ adverse effect" balance using the correct dose, monitoring relevant clinical and laboratory parameters and educating patients.

10
من 62 ـــ الي 68
الملخص

A multivariate calibration method for the analysis of two paracetamol binary mixtures is described. The mixtures are composed of paracetamol in combination either with ascorbic acid or caffeine respectively. The components of the two mixtures show a considerable degree of spectral overlapping (83.1-88.3%). Resolution of the binary mixtures under investigation has been accomplished mainly by using classical least squares (CLS) analysis. The mixtures are simultaneously determined in commercial dosage forms with high accuracy without interference from the commonly encountered excipients. Good recoveries were obtained with both synthetic mixtures and commercial formulations. The obtained results were compared with those obtained from some reported methods and found in good agreement with them.

11
من 69 ـــ الي 72
الملخص

We report a 42-years-old woman presented with isolated cardiac metastasis 2 years after radical hysterectomy for squamous cell carcinoma of the cervix. Magnetic resonance imaging was consistent with primary cardiac myxoma. The original tumor and cardiac metastasis were analyzed for expression of low and high molecular weight cytokeratin, ki-67, and p 53. The first intraoperative frozen sections exhibited only prominent myxomatous stroma, leading to an initial impression of myxoma. Metastatic squamous cell carcinoma to the right atrium can mimic atrial myxoma by MRI. Furthermore, a myxoid, proliferative stromal reaction can lead to an initial misdiagnosis of atrial myxoma. The literature on the rare occurrence of isolated metastasis of cervical squamous cell carcinoma to the heart is reviewed.

12
من 73 ـــ الي 74
13
من 75 ـــ الي 79
14
من 80 ـــ الي 82
الملخص

Optimal concentration of tannic acid was found to be 0.1 to 0.4% to prepare IHA reagent for .the diagnosis of human hydatidosis. Higher concentrations of tannic acid result/clumping, inhibition of sheep erythrocytes and appeared unsuitable for the preparation of IHA reagent.

15
من 83 ـــ الي 84
الملخص

A total of 102 surgically confirmed hydatid patients were serodiagnosed for the presence of antibodies against cystic echinococcosis. Enzyme linked immunosorbent assay (ELISA) was employed using antigens prepared from sheep hydatid fluid, and protoscolices and brood capsules of sheep hydatid cysts. ELISA yield more positive reactions with somatic hydatid antigens (99.01%) that hydatid fluid antigens (95.09%). None of the sera from 30 University students showed positive reactively with hydatid fluid and somatic hydatid antigens.

16
من 85 ـــ الي 90
الملخص

The present study aims to detect the possibility of sex discrimination from humeral measurements in Egyptians. One hundred normal right humeri were taken from one hundred cadavers (54 males and 46 females) above 20 years of age and belong to the Egyptian population. Six measurements of maximum length, vertical head diameter, midshaft circumference, minimum midshaft diameter, maximum midshaft diameter and epicondylar breadth were taken for each humerus. The measurements were statistically analyzed. The results revealed that the measurements of males were significantly higher than those of females (P < 0.001). Maximum length was the most discriminating variable in sex determination with 90% rate of accuracy, followed by midshaft circumference (86%) then minimum midshaft diameter (82%). Combination of two variables revealed that minimum midshaft diameter with epicondylar breadth gave the highest rate of accuracy for correct sex prediction with accuracy rate of 88%. The results of the study can help in the prediction of sex from the humerus in Egyptians when other human remains, suitable for sex determination, are not available.

17
من 91 ـــ الي 100
الملخص

not found

18
من 101 ـــ الي 102
الملخص

not found

19